| 早期子宫肉瘤的术后放疗临床分析 |
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| 作者:刘兰芳,… 文章来源:《中国癌症杂志》 点击数: 更新时间:2005-5-17 |
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[摘要] 目的:探讨早期子宫肉瘤术后辅助放疗对局部控制率和生存率的影响。
方法:回顾性分析我院1969年4月~1999年10月收治的子宫肉瘤76例的临床资料,Ⅰ期49例,Ⅱ期27例,其中单纯手术组34例,术后放疗组42例。
结果:二年和五年的无瘤生存率,单纯手术组分别为38.2%和26.5%,本后放疗组为 69.0%和57.1%。二年和五年盆腔局部复发,手术组分别为52.9%和64.7%,术后放疗组分别为26.2%和28.6%.二年和五年总的生存率手术组为83.4%和47.0%,术后放疗组为83.3%和69.0%。
结论:术后放疗可明显提高局部控制率,减少远处复发,进而提高无瘤生存率和五年生存率。
[关键词] 子宫肉瘤;早期;放射治疗;手术治疗
Abstract Purpose:To study the role of postoperative radiotherapy in early stage uterine sarcomas.
Methods:Retrospective analysis of the impact of radiotherapy on progress-free survival rate (PRS )rate, local recurrence rate (LRR) and overall survival (OS)in stage Ⅰ,Ⅱ uterine sarcomas. 34 cases were treated with surgery alone ,42 cases were treated with postoperative radiotherapy.
Results:The PRS at 2 and 5 years for surgery were 38.2% and 26.5% ,69.0% and 57.1%for postopeative radiotherapy. The LRR at 2 and 5 years treated with surgery were 52.9% and 64.7%,26.2% and 28.6% with adjuvant irradiation. The OS at 2 and 5 years treated with surgery were 83.4%and 47.0%,83.3% and 69.0% with adjuvant radiation.
Conclusions:Postoperative radiotherapy showed a marked increase in the three parameters studied (PRS、 LRR、OS ) for I,II stage uterine sarcomas.
[Key words] uterine sarcomas;early stage;radiotherapy;surgery
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